Last episode
Bending the Rules
s01e10 · 2026-08-13
Running · US
Most Extreme Humans
TLC Reality
What it is
Most Extreme Humans follows people from around the globe living with the world's rarest and most remarkable physical conditions. From a Filipino man whose hands have grown so large he wears wristwatches as rings, to Brazil, where the world's smallest married couple have a combined height under six feet, to a 19-year-old in India living with the ultra-rare condition known as "werewolf syndrome." This series examines what everyday life looks like when the world is not built with your body in mind.
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Episode guide
10 this season · 10 totals01e01 Biggest Hands 2026-06-11 01:00
Biggest Hands
Mark's hands are 20 times bigger than a normal adult male's.
s01e02 Ugliest Man 2026-06-18 01:00
Ugliest Man
Winner of Uganda's Ugliest Man contest, Godfrey has a rare disorder that has left him disfigured. With 10 children, a new baby on the way, and his condition worsening, he is seeking medical answers that will determine his future.
s01e03 Upside Down with a Twist 2026-06-25 01:00
Upside Down with a Twist
In Brazil, Claudio lives with a condition that bent his head backward; ahead of his 50th birthday, he wants to climb a sacred mountain; in Norway, Birgitte is training for the next Paralympics.
s01e04 Peaks and Valleys 2026-07-02 01:00
Peaks and Valleys
Life defined by height: in Turkey, the world's tallest woman lives with an unknown genetic condition linked to extreme growth and fragile bones, while in Brazil, the world's shortest couple navigate dwarfism and its physical challenges.
s01e05 Face to Face 2026-07-09 01:00
Face to Face
Milagros lives with tumors so heavy that her face droops down to her torso; after hiding away, a health scare is forcing her out into the world; twenty-one-year old Lizzie is preparing to live independently even after tumors have grown over her eyes.
s01e06 Hair Today, Gone Tomorrow? 2026-07-16 01:00
Hair Today, Gone Tomorrow?
In rural Indian, Lalit's face and body has been thickly covered in hair since the day he was born.
s01e07 Skin in the Game 2026-07-23 01:00
Skin in the Game
Mahfuza and Nelly are living with Harlequin ichthyosis, one of the world's rarest and most severe skin conditions; Mahfuza prepares for her first boxing match; Nelly fully supports her friend but worries that the high risks may outweigh the rewards.
s01e08 Keep Calm and Girdle On 2026-07-30 01:00
Keep Calm and Girdle On
Summer has macromastia, a condition that causes her breasts to keep growing. With constant pain in her back and neck from breasts that are now a third of her overall body weight, Summer travels from Scotland to Los Angeles looking for answers.
s01e09 On My Side 2026-08-06 01:00
On My Side
Ecuadorian conjoined twins Jose Luis and Jose Armando leave their home and family to get advanced medical care for a chance at independence. Teenaged Thai conjoined twins Pin and Pan must navigate their ongoing differences they prepare for adulthood.
s01e10 Bending the Rules 2026-08-13 01:00
Bending the Rules
In Indonesia, Dimas dreams of becoming a martial arts warrior, but his family worries the training will harm his oddly bendy body; in Colombia, Herson's backward-bending knees are failing, and he questions his dream of proposing to his girlfriend.